NFL Week 13 Odds With Football Spreads Moneylines And Totals

This weekend's slate in the NFL is absolutely loaded as playoff-bound and playoff-fringe teams square off. NFL Week 13 odds have been posted by sportsbooks and there are some intriguing lines. The Bills and Patriots kicked off the week with Buffalo covering the -4 spread rather easily with a 24-10 road victory. Sunday will feature the Titans +4.5 at Eagles -4.5 as well as the Dolphins +4 at 49ers -4, Chiefs -2 at Bengals +2 and Jets +3 at Vikings -3.

Betting info for all of these NFL games are available below.

Legal online sportsbooks have revealed NFL Week 13 odds with point spreads, moneylines and totals available to bet on. Check out lines for every game below.

The largest spread when looking at NFL Week 13 odds Thursday morning was the Colts +10.5 at the Cowboys -10.5. Other sizable lines include the Seahawks -7.5 at the Rams +7.5 and the Broncos +8.5 at the Ravens -8.5.

The Bills won their first division game of the season as they went into Gillette Stadium and smashed the Patriots, 24-10. Buffalo covered a -4 spread and the game went under the 44-point projected total.

The Steelers went on the road Monday night at took down the Colts, 24-17. The Falcons suffered another close loss this past Sunday, falling to the Commanders by a 19-13 score on Sunday on a late interception off a tipped pass.

The Falcons got another adequate but not quite good enough passing performance from Marcos Mariota, who threw for just 174 yards with a touchdown and interception against Washington. Head coach Arthur Smith has stated he’ll keep Mariota in the starting role as long as Atlanta is in contention, and with the dilapidated state of the NFC South, the Falcons remain very much in the mix for the division crown despite their 5-7 mark.

The Steelers were +1.5 underdogs in most spots ahead of their Monday night game and that spread was nudged to Pittsburgh +1 following their victory over the Colts.

The Packers fought hard and had to deal with an early Aaron Rodgers exit due to what's now being labeled a rib injury, but they ultimately fell to the Eagles on Sunday night by a 40-33 score. The Bears had to roll with Trevor Siemian at quarterback due to Justin Fields’ shoulder injury, and they fell to the Jets at MetLife Stadium by a 31-10 score.

Rodgers’ overall health – he's also dealing with a fractured thumb — will naturally be a subject of extensive scrutiny this coming week. Although he's undergoing further testing Monday, a punctured lung was already ruled out by initial X-rays, and Rodgers has said he intends to play in this Week 13 matchup at a Soldier Field venue he's enjoyed no shortage of success in. Jordan Love completed six of nine attempts for 103 yards and a touchdown in emergency duty Sunday night, however, so Green Bay's offense would likely be in fairly good hands were the less-than-100-percent Rodgers forced to sit out.

The Bears naturally have their own health concerns at quarterback, but Fields could be back for this game after managing to practice on a limited basis every day last week. Siemian wasn't a washout against the Jets by any means, especially considering the quality of defense he was facing in a tough road environment. The Packers are best attacked on the ground anyhow, giving up 154.9 rushing yards per road game after Miles Sanders and Jalen Hurts both easily eclipsed 100 yards against them Sunday night.

Even with the uncertainty regarding both quarterbacks, the Packers are 2.5-point road favorites on NFL Week 13 odds as the week begins.

The Jaguars wouldn't quit Sunday and it paid off, as they nipped the visiting Ravens by a 28-27 score. The Lions fought equally hard on Thanksgiving against the Bills, but they fell on a late field goal, 28-25.

Trevor Lawrence raised his passing yardage total over that of the prior game for the fourth straight time Sunday, finishing with a season-high 321 yards and throwing clutch touchdown and two-point conversion passes with 14 seconds remaining to seal the comeback victory. Travis Etienne's early exit with a foot injury is naturally concerning, but a matchup for Lawrence and his pass catchers against a Lions team allowing an NFL-high 292.7 passing yards per home game sets up extremely well.

Detroit's ability to hang nearly point for point with Buffalo is the latest example of Dan Campbell's squad's improvement, and their matchup is also highly appealing by the numbers. The Jaguars have been especially vulnerable on defense when traveling, allowing nearly 90 passing yards per game more on the road (288.7) than at home (199.4). Jared Goff has been playing progressively better as the season has unfolded, and he could see rookie Jameson Williams (knee) make his NFL debut in this contest.

In a game that could be one of the most competitive of the week, the Lions are one-point home favorites in NFL Week 13 odds.

The Jets made the switch to Mike White at quarterback and it paid off handsomely Sunday, as he put together a 300-yard, three-touchdown effort to topple the Bears, 31-10. The Vikings were able to outlast the Patriots, 33-26, on Thanksgiving Night, bouncing back four days after taking a 40-3 walloping from the Cowboys.

White showed excellent command of the offense while hitting 10 different targets. New York did lose Michael Carter to an in-game ankle injury, yet the combination of rookie Zonovan Knight and Ty Johnson rushed 131 yards and a touchdown (Johnson) on 19 carries. The air attack should be in an especially favorable position against the Vikings defense, which is giving up the third-most passing yards per home game (277.5).

Minnesota will have the rest advantage coming into this contest, and it's undoubtedly very welcome considering the tough task the Jets defense represents. New York has 12 interceptions and 34 sacks through 11 games, and Cousins has taken 28 sacks overall. The potential Justin Jefferson-Sauce Gardner matchup should be one of the most fascinating of the entire week to watch, and how it plays out could well be the pivot point for this game.

In a nod to the legitimacy of the Jets, the Vikings are just standard three-point home favorites in NFL Week 13 odds as of Monday afternoon.

The Commanders were able to squeak out another unaesthetic win Sunday, getting past the Falcons by a 19-13 score to move to 7-5. The Giants were forced to go into battle against the Cowboys on Thanksgiving with an especially short-handed receiving corps and came up short, 28-20.

There's rarely anything pretty about Taylor Heinicke's game, but he undeniably gets results. He and his teammates will get their first up-close look at a revamped Giants defense that's been one of the tougher ones in the league to pass against, especially at home. New York is allowing just 190.8 passing yards per home game and a miserly 57.6 percent completion rate in that split, but the news is better for the Brian Robinson-Antonio Gibson backfield tandem – the G-Men are surrendering 157.2 rushing yards per home contest.

The Giants will still have a short-handed pass-catching crew for Sunday's contest since rookie Wan’Dale Robinson is out of action the rest of the season due to his torn ACL, which may leave New York less than well equipped to take advantage of a Commanders defense that sometimes allows chunk plays through the air. Meanwhile, Saquon Barkley will have a daunting matchup on the ground, as Washington allows only 108.4 rushing yards per game.

Despite New York's rest/homefield advantage, the Giants are notably 1.5-point home underdogs in NFL Week 13 odds as the week starts.

The Titans welcomed in a Bengals team missing both Joe Mixon (concussion) and Ja’Marr Chase (hip) on Sunday and still fell just short by a 20-16 margin. The Eagles likely got more than they bargained for from the Packers on Sunday night before prevailing, 40-33.

Tennessee's offense will have some useful film to evaluate on the Eagles defense after Philly's last three games, as they’ve given up 32 and 33 points in two of those contests. The Titans do have the luxury of coming at the Eagles with some balance, considering what Derrick Henry is capable of doing on the ground. The Eagles have been below average against the run, giving up 120.7 rushing yards per contest and 4.7 yards per rush attempt overall. The air attack figures to have a much tougher challenge given Philadelphia's typically impressive cornerback play, but rookie receiver Treylon Burks is showing very well for Tennessee in the last several games.

Jalen Hurts offered a reminder of his elite rushing ability in Sunday night's win, rattling off a career-high 157 yards on the ground to go along with 153 passing yards and a pair of touchdowns through the air. The Titans have been a much more giving pass defense on the road while surrendering the second-most passing yards per road game (289.5), and with A.J. Brown facing his old squad and Tennessee yielding an NFL-low 59.5 rushing yards per away contest, this could be a game where Philly's passing attack comes to life.

The Eagles are 5.5-point home favorites in NFL Week 13 odds as the week begins.

The Broncos’ nightmare of a season continued Sunday, with Denver falling to the lowly Carolina Panthers by a 23-10 score. The Ravens encountered some frustration in their own right, blowing a late lead to drop a 28-27 decision to the Jaguars.

Russell Wilson slogged through another ugly performance Sunday as Denver fell to 3-8, including 1-5 on the road. Wilson threw for only 142 yards, took three sacks and finished with a 29.1 quarterback rating, a microcosm of his forgettable first season in Denver. While the Ravens have been far easier to pass against than run on, it may not matter much in this matchup unless at least Jerry Jeudy (ankle) is able to return for Denver.

The Ravens should have the luxury of attacking through their preferred method, the ground, in this matchup. The Broncos defense certainly steers action toward the run by allowing just 184.7 passing yards per game and a 61.4 percent completion rate. In contrast, Denver is giving up 133.3 rushing yards per road contest, and with Gus Edwards looking back to health in his return Sunday, he could be in for a busy day.

Baltimore is unsurprisingly a comfortable 8.5-point home favorite on NFL Week 13 odds as the week begins.

The Browns were able to pull off a rousing overtime win in Jacoby Brissett's scheduled final game as the starter, recording a 23-17 victory over the Buccaneers. The Texans fell to the Dolphins by a 30-15 score, with Kyle Allen taking over as the starter for Davis Mills.

The overarching story for this game is naturally the return of Deshaun Watson to regular-season action and the fact he’ll be doing it in the city where all of the significant controversy surrounding him originates. Watson did participate in training camp, played in preseason games and has been back at practice since earlier in November, so he’ll have knocked off some rust. The matchup will at least be a soft landing in theory, especially since the Texans’ run defense should give coach Kevin Stefanski the luxury of leaning heavily on the ground attack.

Allen didn't fare terribly against the Dolphins from a statistical standpoint, but he also accumulated a lot of his production after the game was completely out of hand. The Houston offense isn't likely to demonstrate much improvement until it can presumably be retooled in the offseason, but what is likely its most talented member, rookie running back Dameon Pierce, will at least have a good matchup in theory against a Cleveland defense conceding a whopping 156.4 rushing yards per road contest.

The Browns are unsurprisingly touchdown favorites for Watson's return to start the week.

The Seahawks took a tough 40-34 overtime loss to the Raiders at home in Week 12, one in which Josh Jacobs accumulated an astounding 303 total yards from scrimmage and two TDs, including the game-winning score. The drastically short-handed Rams were predictably beaten by the Chiefs at Arrowhead, although by a smaller margin than many may have predicted, 26-10.

Geno Smith did make a couple of mistakes Sunday but threw for over 300 yards with rookie running back Kenneth Walker mostly stymied on the ground. It could be another busy day for the veteran quarterback in this matchup, considering L.A. has mostly been a brick wall against the run but has shown vulnerability to the pass at times.

Bryce Perkins drew the start for Matthew Stafford (neck) in Sunday's game and didn't acquit himself poorly based on what he was allowed to do, generating 144 total yards and throwing a touchdown, albeit alongside a pair of picks. Even if Stafford is able to make it back for this game, he’ll naturally be working with a short-handed receiving crew that may also be down Allen Robinson (ankle) in addition to Cooper Kupp (IR-ankle). Meanwhile, Seattle's defense wasn't as poor on a per-play basis Sunday as Jacobs’ numbers might imply, as 86 of his rushing yards came on his game-ending touchdown run.

With Stafford uncertain as the week begins, the Seahawks are notably as much as 8-point road favorites against the defending champs.

The Dolphins continued to stay in the thick of the AFC East chase Sunday with an expected 30-15 win over the Texans at home. The 49ers also took care of business on their turf, shutting out the Saints by a 13-0 score but losing Elijah Mitchell for multiple weeks due to a knee injury yet again as well.

Tua Tagovailoa needed less than a full game to throw for 299 yards in Sunday's win, one in which he was actually busier than usual with the Texans surprisingly shutting down Jeff Wilson. The talented running back now returns to San Francisco, along with head coach Mike McDaniel, for this interconference matchup that's critical to both teams’ postseason aspirations. Trying to run on San Francisco, especially at home (NFL-low 63.8 RYPG allowed), is typically a thankless endeavor, but Tagovailoa, Tyreek Hill and Jaylen Waddle could be in for a more productive day than many might expect – the Niners are yielding 236.2 passing yards per contest at Levi's Stadium.

Despite plenty of big names, San Fran's offense isn't always the smoothest, and Mitchell's latest absence dings their overall upside despite the fact the team is used to operating without him by this point. Christian McCaffrey naturally makes for an excellent steward of the running game while also offering elite pass-catching production, and he should be back to essentially taking on a voluminous all-purpose role in light of Mitchell's injury. The Niners passing game should also be in for a productive day with the Dolphins secondary giving up 247.2 passing yards per road game and proving especially vulnerable to tight ends.

In what should be one of the games garnering the most betting attention this week, Miami is just a 3.5-point road underdog in NFL Week 13 odds.

The Chiefs had a bit more trouble with the Rams than may have been expected Sunday, but they ultimately prevailed by a 26-10 score. The Bengals went into an extremely tough road matchup against the Titans without two of their biggest weapons and still prevailed, 20-16.

The Chiefs operated without Clyde Edwards-Helaire (IR-ankle) and Kadarius Toney (hamstring) for Sunday's game, and it remains to be seen if the latter will be able to return for this contest. KC's offense still piled up plenty of yards against Los Angeles, and Mahomes could heavily target a Bengals pass defense that isn't as good with top corner Chidobe Awuzie (knee) lost for the season.

The Bengals will hope to ideally get both Joe Mixon (concussion) and Ja’Marr Chase (hip) back for this game, as they figure to need a full arsenal to ensure they can keep pace with Mahomes and company. While the Chiefs have played especially tough against the run on the road, the matchup through the air against the KC defense isn't prohibitive by any stretch – KC is allowing 264.4 passing yards per away contest.

In what should be another fascinating late-window matchup, it's the Chiefs that are 2-to-2.5-point favorites in NFL Week 13 odds as the week starts.

The Chargers gambled and reaped the rewards in Week 12, as a late two-point conversion gave Los Angeles a 25-24 win over the Cardinals on the road. The Raiders garnered success in thrilling fashion also, notching a 40-34 overtime win against the Seahawks on the strength of Josh Jacobs’ record-setting day.

Justin Herbert threw for 279 yards and three touchdowns in the Week 1 win over the Raiders, even with Keenan Allen exiting that game early with the hamstring injury that's cost him a substantial portion of the season. The veteran wideout has been back in the fold over the last two games without setbacks, but Herbert may have to go into this rematch without Mike Williams, who missed Sunday's game with ankle injury. Fortunately for the Bolts’ air attack, Joshua Palmer and DeAndre Carter have both stepped up their contributions in recent weeks, and the Raiders are allowing 253 passing yards per game overall.

Jacobs is seeing a massive workload and thriving with it, and this matchup sets up exceedingly well for him. The Chargers are allowing the most yards per carry to running backs and have 162.7 rushing yards per away game, as well as 167 rushing yards per contest over the last three overall. Derek Carr also put up some good numbers throwing against L.A. in the first meeting (295 yards, two TDs) despite that game having been his first extended action in Josh McDaniels’ system, but he also was picked off three times and won't have Darren Waller (hamstring) or Hunter Renfrow (oblique) this time around.

In what could be one of the most high-scoring games of the day, it's the Chargers checking in as 1.5-to-2.5-point road favorites.

The Colts take the field Monday night against the Steelers to close out the Week 12 slate and try to move to 2-1 under interim head coach Jeff Saturday. The Cowboys will come in with a rest advantage after having improved their record to 8-3 with a 28-20 win over the Giants on Thanksgiving.

Saturday has unsurprisingly shown a true commitment to the running game in the coach's first two games, and that may indeed be the best way to attack this Cowboys defense. Dallas is allowing 138.3 rushing yards per home game, and Jonathan Taylor has clocked 5.3 yards per carry in the last two contests going into Monday night's battle versus Pittsburgh.

The Cowboys offense is clicking on all cylinders at the moment, and a matchup against a good-but-not-elite Colts defense isn't likely to slow them down. Tony Pollard and Ezekiel Elliott worked well in tandem once again against the Giants and are essentially interchangeable parts from game to game that can keep any defense guessing. Meanwhile, Michael Gallup was incorporated more into the air attack versus New York on intermediate routes, which could be key against an Indy secondary that does very well limiting downfield passing.

The Colts are heavy 9-to-9.5-point underdogs for this matchup ahead of their Monday night contest.

The Saints ran into the stingy defense of the 49ers on the road Sunday, leading to a 13-0 loss. The Buccaneers also suffered defeat away from home, struggling badly on offense throughout the second half on the way to a 23-17 loss in overtime to the Browns.

The Saints continued to roll with Andy Dalton and a sprinkle of Taysom Hill at quarterback Sunday without much success, and it would certainly be interesting if head coach Dennis Allen elected to pivot to Jameis Winston for this game given the setting and the quarterback's history with the Buccaneers. Tampa Bay's defense, despite its ample talent, simply hasn't been special against the run or pass this season, so Alvin Kamara and the rest of New Orleans’ skill position assets could have some success.

The Bucs saw rookie Rachaad White acquit himself well as both runner and receiver Sunday in the losing effort, and even if Leonard Fournette (hip) is healthy enough to return for this game, White could remain the lead back. The Saints’ rush defense played well against Christian McCaffrey on Sunday but was burned by Elijah Mitchell for a long touchdown that was called back due to penalty. Meanwhile, Tom Brady and Chris Godwin flashed quite the connection against Cleveland, but Mike Evans struggled and now faces a New Orleans secondary that's often given him trouble.

In a testament to how unsteady the Bucs have been, they’re just 3.5-point home favorites in NFL Week 13 odds as the week starts.

This table will look at how NFL Week 13 odds are changing in the days leading up to kickoff of each game. More point spreads will be added as we get closer to kickoff.

The initial spreads, moneylines and totals shown here are from Nov. 23.